Welcome to the Yaron Lab

Biotherapeutics Engineering Lab​

Part of the School for Engineering of Matter, Transport and Energy and the Biodesign Institute’s Center for Biomaterials Innovation and Translation.

The Problem

Complex Tissue Injury and Lack of Effective Repair

Injuries are a ubiquitous fact of life. However, despite multiple millions of new cases each year and several billions of dollars in annual health care costs, there are no effective treatments for many types of complex injuries, such as those in the skin and spinal cord.

A complex diagram of a human body attempting to recover from injury. Boilogical processes described in various callouts within the diagram

Our Approach

1. Development of novel biomaterial scaffolds 

We engineer biomaterials with enhanced and expanded functionality to promote tissue repair and regeneration.

2. Controlled delivery of bioactives

We develop methods to delivery bioactives with the goal of treating tissues with “the right drug at the right time” in order to stimulate reparative pathways.

3. Identification and development of novel bioactive agents

We reverse engineer dysfunctional signaling observed in diseased states and pro-healing pathways stimulated by biomaterials to facilitate target identification for novel bioactives.

Image: Spinal cord injury in rats treated with a biodegradable and injectable chitosan and collagen hydrogel with sustained delivery of the immune-modulating, virus-derived biologic Serp-1. Read more at  J. Clin. Med. 2020, 9(4), 1221

Principal Investigator

Jordan R. Yaron, PhD

Assistant Professor

School for Engineering of Matter, Transport and Energy

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