To diagnose Alzheimer’s disease (AD) and related dementias, the assessment of both cognition and daily functioning are necessary. While numerous validated tests of global and domain-specific cognition are available, measures of daily functioning are lacking, with most relying on subjective reports from the patient or a collateral/informant. While performance-based measures of daily functioning are more objective and do not require collateral input, existing tests are very time-consuming and require specialized training, with none rising to the level of a gold standard in clinical practice nor clinical trials. The Motor Rehabilitation and Learning Lab at Arizona State University (directed by Dr. Sydney Schaefer) has been working to address the need for quick assessments that can evaluate older adults for impaired daily function that do not require a collateral and are objective. The benefit of such a test would help identify patients at elevated risk for developing AD or related dementias, which could assist in enriching prevention trials or directing patients to appropriate treatments. Furthermore, quick objective measures of daily functioning are needed as co-primary endpoints for AD clinical trials to better quantify the impact of emerging therapies on patients’ activities of daily living. In response to this need, Dr. Schaefer and her research team have developed a novel brief (~5 minutes) performance-based test that can be administered without collateral input. This test is objective and simple, requiring no extensive training/equipment, wearable technology, or apps, making it highly feasible for widespread use and remote testing. Many Longevity participants also find the test to be quite fun! Dr. Schaefer’s published work to date has demonstrated the test’s sensitivity and specificity to AD symptoms and pathology, as well as its ability to predict cognitive and functional decline without the need for normalizing scores based on sex, education, or ethnicity. Emerging data from the Longevity Study are helping develop normative test scores and quantify typical amounts of annual change in test scores, along with comparing how scores relate to quality of life and caregiver burden. The lab’s long-term goal is to develop an objective, easy-to-administer assessment of cognition and daily functioning for use in dementia clinical practice and clinical trials.