{"id":222,"date":"2024-08-29T09:42:53","date_gmt":"2024-08-29T16:42:53","guid":{"rendered":"https:\/\/labs.engineering.asu.edu\/yaron\/?page_id=222"},"modified":"2025-05-06T23:59:14","modified_gmt":"2025-05-07T06:59:14","slug":"home-page","status":"publish","type":"page","link":"https:\/\/labs.engineering.asu.edu\/yaron\/","title":{"rendered":"Home page"},"content":{"rendered":"<div class=\"uds-hero-md alignfull has-btn-row \" style=\"margin-bottom:var(--wp--preset--spacing--uds-size-8);\"><div class=\"hero-overlay\"><\/div><img loading=\"lazy\" decoding=\"async\" width=\"418\" height=\"418\" src=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/scratch-flux-1.gif\" class=\"hero\" alt=\"\" \/><div class=\"acf-innerblocks-container\">\n\n\n\n<h1 class=\"wp-block-heading has-white-color has-text-color\">Welcome to the <span class=\"highlight-gold\">Yaron Lab<\/span><\/h1>\n\n\n\n<div class=\"wp-block-group content is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"has-white-color has-text-color wp-block-paragraph\">Biotherapeutics Engineering Lab\u200b<\/p>\n<\/div>\n\n<\/div><\/div>\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-930feb06 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<div class=\"wp-block-columns has-white-background-color has-background is-layout-flex wp-container-core-columns-is-layout-2ee30c1a wp-block-columns-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\"><strong>Part of the <a href=\"https:\/\/semte.engineering.asu.edu\/\"><strong>School for Engineering of Matter, Transport and Energy<\/strong><\/a> and the Biodesign Institute\u2019s&nbsp;<a href=\"https:\/\/biodesign.asu.edu\/biomaterials-innovation-and-translation\/\"><strong>Center for Biomaterials Innovation and Translation<\/strong><\/a>.<\/strong><\/h4>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:34px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-columns has-white-background-color has-background is-layout-flex wp-container-core-columns-is-layout-be91d895 wp-block-columns-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\"><strong><span class=\"highlight-gold\"><strong><span class=\"highlight-gold\">The Problem<\/span><\/strong><\/span><\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Complex Tissue Injury and Lack of Effective Repair<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Injuries are a ubiquitous fact of life. However, despite multiple millions of new cases each year and several billions of dollars in annual health care costs, there are no effective treatments for many types of complex injuries, such as those in the skin and spinal cord.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<figure class=\"wp-block-image size-large\" style=\"margin-right:var(--wp--preset--spacing--uds-size-1);margin-left:var(--wp--preset--spacing--uds-size-1)\"><img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"1245\" src=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-1500x1245.png\" alt=\"A complex diagram of a human body attempting to recover from injury. Boilogical processes described in various callouts within the diagram\" class=\"wp-image-27\" srcset=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-1500x1245.png 1500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-500x415.png 500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-1000x830.png 1000w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-1536x1274.png 1536w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Untitled-17-2048x1699.png 2048w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns has-white-background-color has-background is-layout-flex wp-container-core-columns-is-layout-0acba196 wp-block-columns-is-layout-flex\" style=\"margin-top:var(--wp--preset--spacing--uds-size-12);margin-bottom:var(--wp--preset--spacing--uds-size-12)\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\"><strong><span class=\"highlight-gold\">Our&nbsp;Approach<\/span><\/strong><\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">1. <strong>Development of novel biomaterial scaffolds<\/strong>&nbsp;<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">We engineer biomaterials with enhanced and expanded functionality to promote tissue repair and regeneration.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">2. <strong>Controlled delivery of bioactives<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">We develop methods to delivery bioactives with the goal of treating tissues with &#8220;the right drug at the right time&#8221; in order to stimulate reparative pathways.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>3. Identification and development of novel bioactive agents<\/strong><\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">We reverse engineer dysfunctional signaling observed in diseased states and pro-healing pathways stimulated by biomaterials to facilitate target identification for novel bioactives.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-style-uds-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"952\" src=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2-1500x952.png\" alt=\"\" class=\"wp-image-33\" srcset=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2-1500x952.png 1500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2-500x317.png 500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2-1000x635.png 1000w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2-1536x975.png 1536w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2024\/05\/Picture1-2.png 1617w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/><figcaption class=\"wp-element-caption\">Image: Spinal cord injury in rats treated with a biodegradable and injectable chitosan and collagen hydrogel with sustained delivery of the immune-modulating, virus-derived biologic Serp-1. Read more at&nbsp; <a style=\"font-size: 0.75rem; text-align: var(--bs-body-text-align); display: inline !important;\" href=\"https:\/\/www.mdpi.com\/2077-0383\/9\/4\/1221\"><em>J. Clin. Med.<\/em>&nbsp;<strong>2020<\/strong>,&nbsp;<em>9<\/em>(4), 1221<\/a><\/figcaption><\/figure>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column has-gray-1-background-color has-background is-layout-flow wp-container-core-column-is-layout-1d994d32 wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--uds-size-2);padding-right:var(--wp--preset--spacing--uds-size-2);padding-bottom:var(--wp--preset--spacing--uds-size-2);padding-left:var(--wp--preset--spacing--uds-size-2);flex-basis:33.33%\">\n<h3 class=\"wp-block-heading\">Principal Investigator<\/h3>\n\n\n<div class=\"uds-person-profile is-style-small\" style=\"margin-bottom:var(--wp--preset--spacing--uds-size-6);\"><div class=\"profile-img-container\"><div class=\"profile-img-placeholder\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-150x150.jpg\" class=\"profile-img\" alt=\"\" srcset=\"https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-150x150.jpg 150w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-500x500.jpg 500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-1500x1500.jpg 1500w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-1000x1000.jpg 1000w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron-1536x1536.jpg 1536w, https:\/\/labs.engineering.asu.edu\/yaron\/wp-content\/uploads\/sites\/215\/2025\/03\/2024-Headshot-Yaron.jpg 2007w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/div><\/div><div class=\"person\"><div class=\"person-name\"><h3 class=\"person-name\">Jordan R. Yaron, PhD<\/h3><\/div><div class=\"person-profession\"><h4><span>Assistant Professor<\/span><\/h4><h4><span>School for Engineering of Matter, Transport and Energy<\/span><\/h4><\/div><ul class=\"person-contact-info\"><li><a href=\"mailto:jyaron@asu.edu\" aria-label=\"Mail to: jyaron@asu.edu\" data-ga-event=\"link\" data-ga-action=\"click\" data-ga-name=\"onclick\" data-ga-type=\"internal link\" data-ga-region=\"main content\" data-ga-section=\"Jordan R. Yaron, PhD\" data-ga=\"jyaron@asu.edu\">jyaron@asu.edu<\/a><\/li><\/ul><a href=\"https:\/\/search.asu.edu\/profile\/861524\" class=\"btn btn-maroon btn-md\">View profile<\/a><\/div><\/div>\n\n\n<h3 class=\"wp-block-heading\" style=\"margin-bottom:0;margin-left:0\">Lab News<\/h3>\n\n\n\n<div class=\"wp-block-query is-layout-flow wp-block-query-is-layout-flow\"><ul class=\"is-style-default wp-block-post-template is-layout-flow wp-block-post-template-is-layout-flow\"><li class=\"wp-block-post post-489 post type-post status-publish format-standard hentry category-publications category-lab-news\">\n<h4 class=\"wp-block-post-title\"><a href=\"https:\/\/labs.engineering.asu.edu\/yaron\/2025\/12\/serpinb3-study-published-in-pnas\/\" target=\"_self\" >SerpinB3 study published in PNAS<\/a><\/h4>\n\n<div class=\"wp-block-post-date\"><time datetime=\"2025-12-12T13:07:45-07:00\">December 12, 2025<\/time><\/div>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Our work on the fundamental physiologic role for SerpinB3 in wound healing has been published in the Proceedings of the National Academy of Sciences. This&hellip; <\/p><\/div>\n<\/li><li class=\"wp-block-post post-459 post type-post status-publish format-standard hentry category-uncategorized\">\n<h4 class=\"wp-block-post-title\"><a href=\"https:\/\/labs.engineering.asu.edu\/yaron\/2025\/08\/the-yaron-lab-receives-2-million-nih-r01-grant-to-pursue-disease-mechanisms-and-therapeutic-targets-in-psoriasis\/\" target=\"_self\" >The Yaron Lab receives $2 Million NIH R01 grant to pursue disease mechanisms and therapeutic targets in psoriasis<\/a><\/h4>\n\n<div class=\"wp-block-post-date\"><time datetime=\"2025-08-30T13:04:58-07:00\">August 30, 2025<\/time><\/div>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Dr. Yaron has received a 5-year Stephen I. Katz R01 to investigate novel disease mechanisms and therapeutic targets in psoriasis. This work is a joint&hellip; <\/p><\/div>\n<\/li><li class=\"wp-block-post post-452 post type-post status-publish format-standard hentry category-uncategorized\">\n<h4 class=\"wp-block-post-title\"><a href=\"https:\/\/labs.engineering.asu.edu\/yaron\/2025\/06\/chintan-shah-accepts-internship-at-alcon\/\" target=\"_self\" >Chintan Shah accepts internship at Alcon<\/a><\/h4>\n\n<div class=\"wp-block-post-date\"><time datetime=\"2025-06-16T11:20:47-07:00\">June 16, 2025<\/time><\/div>\n\n<div class=\"wp-block-post-excerpt\"><p class=\"wp-block-post-excerpt__excerpt\">Congratulations to MS student Chintan Shah on accepting a summer internship at Alcon Inc., a Swiss-American pharmaceutical and medical device company specializing in eye care&hellip; <\/p><\/div>\n<\/li><\/ul>\n\n<nav class=\"wp-block-query-pagination is-layout-flex wp-block-query-pagination-is-layout-flex\" aria-label=\"Pagination\">\n\n\n<div class=\"wp-block-query-pagination-numbers\"><span aria-current=\"page\" class=\"page-numbers current\">1<\/span>\n<a class=\"page-numbers\" href=\"?query-4-page=2\">2<\/a><\/div>\n\n<a href=\"\/yaron\/wp-json\/wp\/v2\/pages\/222?query-4-page=2\" class=\"wp-block-query-pagination-next\">Next Page<\/a>\n<\/nav>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p class=\"mb-2\">Part of the School for Engineering of Matter, Transport and Energy and the Biodesign Institute\u2019s&nbsp;Center for Biomaterials Innovation and Translation. The Problem Complex Tissue Injury and Lack of Effective Repair Injuries are a ubiquitous fact of life. However, despite multiple millions of new cases each year and several billions of dollars in annual health care&#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-222","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/pages\/222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/comments?post=222"}],"version-history":[{"count":0,"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/pages\/222\/revisions"}],"wp:attachment":[{"href":"https:\/\/labs.engineering.asu.edu\/yaron\/wp-json\/wp\/v2\/media?parent=222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}